One of the special features of Our Lady's High School is its War Memorial Chapel, built to commemorate former staff and pupils of Our Lady's and St Joseph's High Schools who lost their lives during the Second World War.

Funds to build the original Chapel were raised by parents, staff, and pupils of the school and by the local community. The dedication of The War Memorial Chapel, on its original site in the former Our Lady's High School buildings in Airbles Street, took place on the 14th June 1949.

Each November, Right Rev. Joseph Devine, Bishop of Motherwell, celebrates a Memorial Mass in the Chapel, attended by relatives of those who are commemorated there.

The interior design of the Chapel owes much to the work of Sadie McLellan and Walter Pritchard. The Chapel's features include:

• a statue of the Virgin and Child in copper and brass
• a stained glass window behind the statue
• religious murals
• Memorial Plaque and Book of Remembrance
• military insignia, flags and regimental badges

Recent additions to the Chapel include:

• a millennium tapestry containing the signatures of the school's staff and pupils in the year 2000
• a millennium time capsule
• direct access to the school's  sensory garden which is being developed with a dual role as a garden of remembrance

The Chapel continues to play an important role in the daily religious and spiritual life of Our Lady's High School.